Education & Positions

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Full professor (2019.09-present)

Department of Bionanotechnology (graduate school)

Hanyang University

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Assistant and associate professor (2011.09-2019.08)

Department of Bionanotechnology (graduate school)

Hanyang University

 

Research associate in Organic Chemistry (2006.03-2011.02)

University of Wisconsin-Madison (UW-Madison)

Advisor: Professor Samuel H. Gellman

 

Ph. D. in Organic Chemistry (2000.03-2006.02)

Seoul National University (SNU)

Advisor: Professor Junghun Suh

 

Bachelor of Science in Chemistry (1994-2000; summa cum laude)

Seoul National University (SNU)

Advisor: Professor Jong-In Hong

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Awards & Honors

2014.10 – POSCO Science Fellowship (Young Professor)

2018.05 – LG Yonam Fellowship (Overseas Research Professor)

2019.05 – Best Research Award of ERICA (2018, research papers)

2022.12 - Samsung Science & Technology (SSTF) Investigator

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Representative papers

[13] H. J. Lee, M. Ehsan, X. Zhang, S. Katsube, C. F. Munk, H. Wang, W. Ahmed, A. Kumar, B. Byrne, C. J. Loland, L. Guan. X. Liu, P. S. Chae* “Development of 1,3-acetonedicarboxylate-derived glucoside amphiphiles (ACAs) for membrane protein study” Chem. Sci.  2022, 13, 5750-5759 (Corresponding author, IF = 9.9).

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[12] H. J. Lee, H. S. Lee, T. Youn, B. Byrne, P. S. Chae* “Impact of novel detergents on membrane protein studies" Chem 2022, 8, 980-1013 (Corresponding author, IF = 25.8).  

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[11] M. Das, F. Mahler, P. Hariharan, H. Wang, Y. Du, J. S. Mortesen, E. Perez, L. Ghani, D. Gluck, H. J. Lee, B. Byrne, C. J. Loland, L. Guan, B. K. Kobilka, S. Keller, P. S. Chae* “Diastereomeric Cyclopentane-based Maltosides (CPMs) as Tools for Membrane Protein Study" J. Am. Chem. Soc. 2020, 142, 21382-21392 (corresponding author, IF = 14.6).

 

[10] L. Ghani, C. F. Munk, X. Zhang, S. Katsube, Y. Du, C. Cecchetti, W. Huang, H. E. Bae, S. Saourous, M. Ehsan, L. Guan, X. Liu, C. J. Loland, B. K. Kobilka, B. Byrne, P. S. Chae* “1,3,5-Triazine-cored maltoside amphiphiles for membrane protein extraction and stabilization” J. Am. Chem. Soc. 2019, 141, 19677-19687 (Corresponding author, IF = 14.7).

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[9] H. E. Bae, Y. Du, P. Hariharan, J. S. Mortensen, K. K. Kumar, B. Ha., M. Das., H. S. Lee, C. J. Loland, L. Guan, B. K. Kobilka, P. S. Chae* “Asymmetric maltose neopentyl glycol amphiphiles for membrane protein study: Effect of detergent asymmetricity on protein stability” Chem. Sci.  2019,10, 1107-1116 (Corresponding author, IF = 9.6).

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[8] A. Sadaf, Y. Du, C. Santillan, J. S. Mortensen, I. Molist, A. B. Seven, P. Hariharan, G. Skiniotis, C. J. Loland, B. K. Kobilka, L. Guan, B. Byrne, P. S. Chae* “Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study” Chem. Sci.  2017, 8, 8315-8324 (Corresponding author, IF = 9.0).

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[7] M. Das, Y. Du, O. Ribeiro, P. Hariharan, J. S. Mortensen, D. Patra, G. Skiniotis, C. J. Loland, L. Guan, B. K. Kobilka, B. Byrne, P. S. Chae*, “Conformationally preorganized diastereomeric norbornane-based maltosides (NBMs) for membrane protein study: Implications of detergent kink for micellar properties” J. Am. Chem. Soc. 2017, 139, 3072-3081. (Corresponding author, IF = 14.3).

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[6] M. Das, Y. Du, N J. S. Mortensen, O. Ribeiro, E. Tikhonova, P. Hariharan, L. Guan, C. J. Loland, B. K. Kobilka, B. Byrne, P. S. Chae*, “Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: Importance of chirality in the linker region” Chem. Sci. 2017, 8, 1169-1177. (Corresponding author, IF = 9.0).

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[5] M. Ehsan, Y. Du, N. J. Scull, E. Tikhonova, J. S. Mortensen, J. Tarrasch, G. Skiniotis, C. J. Loland, L. Guan, B. Byrne, Brian. K. Kobilka, P. S. Chae* “Highly branched penta-saccharide-bearing amphiphiles for membrane protein studies” J. Am. Chem. Soc. 2016, 138 (11), 3789–3796. (Corresponding author, IF = 13.1).

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[4] A. Sadaf, S. Capaldi, E. Tikhonova, J. S. Mortensen, C. J. Loland, L. Guan, B. Byrne, P. S. Chae* “A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study” Chem. Sci. 2016, 7, 1933–1939. (Corresponding author, IF = 9.2).

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[3] S. G. F. Rasmussen, B. T. DeVree, Y. Zou, A. C. Kruse, K. Y. Chung, T. S. Kobilka, F. S. Thian, P. S. Chae, E. Pardon, D. Calinski, J. M. Mathiesen, S. T. A. Shah, J. A. Lyons, M. Caffrey, S. H. Gellman, J. Steyaert, G. Skiniotis, W. I. Weis*, R. K. Sunnahara*, B. K. Kobilka*, “Crystal structure of the b2 Adrenergic Receptor-Gs protein complex“, Nature 2011, 477, 549-555. (cover)

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[2] Chae, P. S.; Gotfryd, K.; Pacyna, J.; Miercke, L. J.; Rasmussen, S. G.; Robbins, R. A.; Rana, R. R.; Loland, C. J.; Kobilka, B.; Stroud, R.; Byrne, B.; Gether, U. and Gellman, S. H., “Tandem Facial Amphiphiles for Membrane Protein Stabilization",. J. Am. Chem. Soc. 2010, 132 (47), 16750–16752.

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[1] Chae, P. S.; Rasmussen, S. G.;Rana, R. R.; Gotfryd, K.; Chandra, R.; Goren, M. A.; Kruse, A. C.; Nurva, S.; Loland, C. J.; Pierre, Y.; Drew, D.; Popot, J. L.; Picot, D.; Fox, B. G.; Guan, L.; Gether, U.; Byrne, B.; Kobilka, B. and Gellman, S. H., “Maltose-neopentyl Glycol (MNG) Amphiphiles for Solubilization, Stabilization and Crystallization of Membrane Proteins",. Nat. Methods 2010, 7, 1003-1008.

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Tel: +82-31-400-5205   Email: pchae@hanyang.ac.kr
Address: room 223 Engineering Building I, 55 hanyangdaehakro, Sangnok-gu, Ansan-si, Gyeonggi-do, Republic of Korea (zip code: 15588)